Design of Microporous Metal Oxide Transistors for Field-Enhanced Biochemical Sensing of the Immune Response

Biosensors are key technologies for understanding the use of implanted devices in the human body and offer the potential to inform surgical procedures as well as deliver long-term information about wear, reliability, and physiological response. Porous structures are important tools for 3D integration of biomaterials with living tissues. Biosensors integrated within porous structures, for example, can provide important data about physiological responses to implantation of new biomaterials.

The project, led by William Scheideler, assistant professor of engineering, Dartmouth College, will develop porous sensors for monitoring the inflammatory response to implanted biomaterials with the goal of furthering our understanding of the human immune response. Scheideler is collaborating with Boston Micro Fabrication, a leader in industrial, micro-precision 3D printing.

The New Hampshire Center for Multiscale Modeling and Manufacturing of Biomaterials (NH BioMade) advances the design and manufacture of biomaterials. The NH BioMade Research Seed Funding Opportunity provides support for faculty and post-doctoral associates at New Hampshire universities and colleges to pursue research questions related to the NH BioMade focus areas. Led by the University of New Hampshire, NH BioMade is supported by a National Science Foundation EPSCoR award (#1757371).